Review





Similar Products

peripheral blood leukocytes  (Qiagen)
99
Qiagen peripheral blood leukocytes
Peripheral Blood Leukocytes, supplied by Qiagen, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/QIAamp+DNA+FFPE+Tissue+Kit/pm42854640-79-7-29
Average 99 stars, based on 1 article reviews
peripheral blood leukocytes - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
myeloperoxidase  (MedChemExpress)
94
MedChemExpress myeloperoxidase
Myeloperoxidase, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/Myeloperoxidase%2C+human+white+blood+cells/pm42810343-285-45-50
Average 94 stars, based on 1 article reviews
myeloperoxidase - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
leukocyte acid phosphatase kit  (ABclonal Biotechnology)
95
ABclonal Biotechnology leukocyte acid phosphatase kit
Leukocyte Acid Phosphatase Kit, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/PHOSPHO2+Rabbit+pAb/pm42520681-86-27-31
Average 95 stars, based on 1 article reviews
leukocyte acid phosphatase kit - by Bioz Stars, 2026-10
95/100 stars
  Buy from Supplier
pan leukocyte panel  (Miltenyi Biotec)
95
Miltenyi Biotec pan leukocyte panel
Pan Leukocyte Panel, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/CD14+Antibody%2C+anti-human%2C+REAfinity/pm42380677-329-44-51
Average 95 stars, based on 1 article reviews
pan leukocyte panel - by Bioz Stars, 2026-10
95/100 stars
  Buy from Supplier
leukocyte scattergrams changes  (Sysmex Corporation)
86
Sysmex Corporation leukocyte scattergrams changes
Leukocyte Scattergrams Changes, supplied by Sysmex Corporation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/changes+leukocyte+scattergrams/pmc13262749-4-0-5
Average 86 stars, based on 1 article reviews
leukocyte scattergrams changes - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
leukocyte separation percoll  (Cytiva Europe)
99
Cytiva Europe leukocyte separation percoll
Leukocyte Separation Percoll, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/Percoll/us12642832-932-1-4
Average 99 stars, based on 1 article reviews
leukocyte separation percoll - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
leukocyte reduction filters rs haemonetics  (Haemonetics)
86
Haemonetics leukocyte reduction filters rs haemonetics
Leukocyte Reduction Filters Rs Haemonetics, supplied by Haemonetics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/efficiency+filter+high+leukocyte+neo1+reduction/pmc13247543-49-6-9
Average 86 stars, based on 1 article reviews
leukocyte reduction filters rs haemonetics - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
leukocytes  (Miltenyi Biotec)
98
Miltenyi Biotec leukocytes
Leukocytes, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/Tumor+Dissociation+Kit%2C+mouse/pmc13255055-180-2-13
Average 98 stars, based on 1 article reviews
leukocytes - by Bioz Stars, 2026-10
98/100 stars
  Buy from Supplier
leukocyte membrane  (Leuko Labs)
86
Leuko Labs leukocyte membrane
Leukocyte Membrane, supplied by Leuko Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/leukocyte+membrane/pmc13142273-258-10-12
Average 86 stars, based on 1 article reviews
leukocyte membrane - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
imbalanced killer immunoglobulin like receptor kir human leukocyte antigen c hla c  (Galectin Therapeutics)
86
Galectin Therapeutics imbalanced killer immunoglobulin like receptor kir human leukocyte antigen c hla c
Disrupted cellular interaction network at the maternal–fetal interface in recurrent pregnancy loss (RPL). This schematic illustrates representative alterations in cell–cell communication associated with immune tolerance failure at the maternal–fetal interface. Under pathological conditions, impaired decidual stromal cell (DSC)-derived transforming growth factor-β (TGF-β) signaling may contribute to loss of the tolerogenic uterine natural killer (uNK) cell phenotype. Reduced Galectin-9 signaling and abnormal uNK–human <t>leukocyte</t> <t>antigen-C</t> <t>(HLA-C)/killer</t> <t>immunoglobulin-like</t> receptor (KIR) interactions may weaken trophoblast support. In parallel, macrophage polarization may shift toward a pro-inflammatory M1-like state, and the balance between regulatory T cells (Treg) and T helper 17 (Th17) cells may become disrupted. These alterations are associated with impaired trophoblast support and increased susceptibility to trophoblast stress and apoptosis. This figure is intended as a conceptual summary of reported cellular interaction abnormalities rather than a definitive mechanistic model. DSCs, decidual stromal cells; FASL, Fas ligand; HLA-C, human leukocyte antigen-C; KIR, killer cell immunoglobulin-like receptor; TGF-β, transforming growth factor-β; Th17, T helper 17 cells; TNFRs, tumor necrosis factor receptors; Treg, regulatory T cells; uNK, uterine natural killer cell.
Imbalanced Killer Immunoglobulin Like Receptor Kir Human Leukocyte Antigen C Hla C, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/leukocyte/antigen+c+c+hla+human+imbalanced+immunoglobulin+killer+kir+leukocyte+like+receptor/pmc13167537-134-12-9
Average 86 stars, based on 1 article reviews
imbalanced killer immunoglobulin like receptor kir human leukocyte antigen c hla c - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier

Image Search Results


Disrupted cellular interaction network at the maternal–fetal interface in recurrent pregnancy loss (RPL). This schematic illustrates representative alterations in cell–cell communication associated with immune tolerance failure at the maternal–fetal interface. Under pathological conditions, impaired decidual stromal cell (DSC)-derived transforming growth factor-β (TGF-β) signaling may contribute to loss of the tolerogenic uterine natural killer (uNK) cell phenotype. Reduced Galectin-9 signaling and abnormal uNK–human leukocyte antigen-C (HLA-C)/killer immunoglobulin-like receptor (KIR) interactions may weaken trophoblast support. In parallel, macrophage polarization may shift toward a pro-inflammatory M1-like state, and the balance between regulatory T cells (Treg) and T helper 17 (Th17) cells may become disrupted. These alterations are associated with impaired trophoblast support and increased susceptibility to trophoblast stress and apoptosis. This figure is intended as a conceptual summary of reported cellular interaction abnormalities rather than a definitive mechanistic model. DSCs, decidual stromal cells; FASL, Fas ligand; HLA-C, human leukocyte antigen-C; KIR, killer cell immunoglobulin-like receptor; TGF-β, transforming growth factor-β; Th17, T helper 17 cells; TNFRs, tumor necrosis factor receptors; Treg, regulatory T cells; uNK, uterine natural killer cell.

Journal: Frontiers in Immunology

Article Title: Multi-omics insights into immune tolerance at the maternal–fetal interface in recurrent pregnancy loss: mechanisms, integration challenges, and translational perspectives

doi: 10.3389/fimmu.2026.1811970

Figure Lengend Snippet: Disrupted cellular interaction network at the maternal–fetal interface in recurrent pregnancy loss (RPL). This schematic illustrates representative alterations in cell–cell communication associated with immune tolerance failure at the maternal–fetal interface. Under pathological conditions, impaired decidual stromal cell (DSC)-derived transforming growth factor-β (TGF-β) signaling may contribute to loss of the tolerogenic uterine natural killer (uNK) cell phenotype. Reduced Galectin-9 signaling and abnormal uNK–human leukocyte antigen-C (HLA-C)/killer immunoglobulin-like receptor (KIR) interactions may weaken trophoblast support. In parallel, macrophage polarization may shift toward a pro-inflammatory M1-like state, and the balance between regulatory T cells (Treg) and T helper 17 (Th17) cells may become disrupted. These alterations are associated with impaired trophoblast support and increased susceptibility to trophoblast stress and apoptosis. This figure is intended as a conceptual summary of reported cellular interaction abnormalities rather than a definitive mechanistic model. DSCs, decidual stromal cells; FASL, Fas ligand; HLA-C, human leukocyte antigen-C; KIR, killer cell immunoglobulin-like receptor; TGF-β, transforming growth factor-β; Th17, T helper 17 cells; TNFRs, tumor necrosis factor receptors; Treg, regulatory T cells; uNK, uterine natural killer cell.

Article Snippet: Furthermore, abnormal uNK–trophoblast interactions have been associated with reduced Galectin-9 expression and imbalanced killer immunoglobulin-like receptor (KIR)–human leukocyte antigen-C (HLA-C) pairing, which may impair trophoblast invasiveness and endothelial remodeling, ultimately contributing to defective spiral artery remodeling and placental perfusion disorders ( , ).

Techniques: Derivative Assay